Tyrocore
The Performance is in the Polymer
Tyrocore™ is REVA’s proprietary polymer invented specifically for bioresorbable scaffolds.
Strong at Its Core
Tyrocore gets its strength from its molecular structure.
Twice as Strong and 10 Times More Ductile than PLLA
Properties of Tyrocore versus PLLA
| Attribute | Tyrocore | PLLA1 | Benefit |
|---|---|---|---|
| Ultimate Tensile Strength | 100-110 MPa | 50-70 MPa | Thinner struts Radial strength |
| Elongation at Break (Ductility) | 120-200% | 2-10% | Single-step inflation Larger expansion range |
| X-Ray Visible | Yes | No | Accurate placement |
A single Fantom Encore scaffold contains < 1% of the iodine found in 1 mL of contrast media
Tyrocore Radiopacity
Naturally Biocompatible
- Tyrocore is derived from the naturally occurring tyrosine amino acid
- Low inflammation, irritation, or calcification during degradation
- Benign degradants are excreted through kidneys and lungs
- Iodine remains safely bound to I2DAT
- Radiolabel ADME study shows I2DAT is safely excreted
- Low lactic acid to support full vessel recovery
- 10 times lower lactic acid release with Tyrocore
Learn more about Tyrocore
EuroPCR 2018 Presentation
Technical Summary
Tyrocore Whitepaper
References:
- Poly (Lactic acid): Synthesis, Structure, Properties, and Applications. Edited by R.Auras, L-T.Lim, S.E.M.Selke, H.Tsuji. 2010 John Wiley & Sons, Inc.; p.141